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1.
Braz J Cardiovasc Surg ; 39(2): e20230231, 2024 Apr 03.
Artigo em Inglês | MEDLINE | ID: mdl-38568942

RESUMO

INTRODUCTION: Protocols for obtaíníng the maxímum threshold pressure have been applied wíth límited precision to evaluate ínspiratory muscle endurance. In thís sense, new protocols are needed to allow more relíable measurements. The purpose of the present study was to compare a new incremental ramp load protocol for the evaluation of ínspíratory muscle endurance wíth the most used protocol in healthy indíviduals. METHODS: This was a prospective cross-sectional study carried out ín a síngle center. Nínety-two healthy indíviduals (43 men [22 ± 3 years] and 49 women [22 ± 3 years]) were randomly allocated to perform: (i) íncremental ramp load protocol and (íí) íncremental step loadíng protocol. The sustained pressure threshold (or maximum threshold pressure), maximum threshold pressure/dynamic strength índex ratío, time untíl task faílure, as well as dífference between the mean heart rate of the last five mínutes of baselíne and the peak heart rate of the last 30 seconds of each protocol were measured. RESULTS: Incremental ramp load protocol wíth small íncreases in the load and starting from mínímum values of strength index was able to evaluate the inspiratory muscle endurance through the maxímum threshold pressure of healthy indívíduals. CONCLUSION: The present study suggests that the íncremental ramp load protocol is able to measure maximum threshold pressure in a more thorough way, wíth less progression and greater accuracy in the load stratification compared to the límited incremental step loading protocol and with a safe and expected cardiovascular response in healthy individuals.


Assuntos
Teste de Esforço , Resistência Física , Masculino , Humanos , Feminino , Resistência Física/fisiologia , Estudos Transversais , Estudos Prospectivos , Músculos Respiratórios/fisiologia , Ensaios Clínicos Controlados Aleatórios como Assunto
2.
Rev. bras. cir. cardiovasc ; 39(2): e20230231, 2024. tab, graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1535542

RESUMO

ABSTRACT Introduction: Protocols for obtaining the maximum threshold pressure have been applied with limited precision to evaluate inspiratory muscle endurance. In this sense, new protocols are needed to allow more reliable measurements. The purpose of the present study was to compare a new incremental ramp load protocol for the evaluation of inspiratory muscle endurance with the most used protocol in healthy individuals. Methods: This was a prospective cross-sectional study carried out in a single center. Ninety-two healthy individuals (43 men [22 ± 3 years] and 49 women [22 ± 3 years]) were randomly allocated to perform: (i) incremental ramp load protocol and (ii) incremental step loading protocol. The sustained pressure threshold (or maximum threshold pressure), maximum threshold pressure/dynamic strength index ratio, time until task failure, as well as difference between the mean heart rate of the last five minutes of baseline and the peak heart rate of the last 30 seconds of each protocol were measured. Results: Incremental ramp load protocol with small increases in the load and starting from minimum values of strength index was able to evaluate the inspiratory muscle endurance through the maximum threshold pressure of healthy individuals. Conclusion: The present study suggests that the incremental ramp load protocol is able to measure maximum threshold pressure in a more thorough way, with less progression and greater accuracy in the load stratification compared to the limited incremental step loading protocol and with a safe and expected cardiovascular response in healthy individuals.

4.
Braz J Cardiovasc Surg ; 38(4): e20220459, 2023 07 04.
Artigo em Inglês | MEDLINE | ID: mdl-37403941

RESUMO

OBJECTIVE: This study aims to investigate the ability of the six-minute walk distance (6MWD) as a prognostic marker for midterm clinical outcomes three months after coronary artery bypass grafting (CABG), to identify possible predictors of fall in 6MWD in the early postoperative period, and to establish the percentage fall in early postoperative 6MWD, considering the preoperative baseline as 100%. METHODS: A prospective cohort of patients undergoing elective CABG were included. The percentage fall in 6MWD was assessed by the difference between preoperative and postoperative day (POD) five. Clinical outcomes were evaluated three months after hospital discharge. RESULTS: There was a significant decrease in 6MWD on POD5 compared with preoperative baseline values (percentage fall of 32.5±16.5%, P<0.0001). Linear regression analysis showed an independent association of the percentage fall of 6MWD with cardiopulmonary bypass (CPB) and preoperative inspiratory muscle strength. Receiver operating characteristic curve analysis revealed that the best cutoff value of percentage fall in 6MWD to predict poorer clinical outcomes at three months was 34.6% (area under the curve = 0.82, sensitivity = 78.95%, specificity = 76.19%, P=0.0001). CONCLUSION: This study indicates that a cutoff value of 34.6% in percentage fall of 6MWD on POD5 was able to predict poorer clinical outcomes at three months of follow-up after CABG. Use of CPB and preoperative inspiratory muscle strength were independent predictors of percentage fall of 6MWD in the postoperative period. These findings further support the clinical application of 6MWD and propose an inpatient preventive strategy to guide clinical management over time.


Assuntos
Ponte de Artéria Coronária , Humanos , Teste de Caminhada , Estudos Prospectivos , Curva ROC , Análise de Regressão
6.
Rev. bras. cir. cardiovasc ; 38(4): e20220459, 2023. tab, graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1449553

RESUMO

ABSTRACT Objective: This study aims to investigate the ability of the six-minute walk distance (6MWD) as a prognostic marker for midterm clinical outcomes three months after coronary artery bypass grafting (CABG), to identify possible predictors of fall in 6MWD in the early postoperative period, and to establish the percentage fall in early postoperative 6MWD, considering the preoperative baseline as 100%. Methods: A prospective cohort of patients undergoing elective CABG were included. The percentage fall in 6MWD was assessed by the difference between preoperative and postoperative day (POD) five. Clinical outcomes were evaluated three months after hospital discharge. Results: There was a significant decrease in 6MWD on POD5 compared with preoperative baseline values (percentage fall of 32.5±16.5%, P<0.0001). Linear regression analysis showed an independent association of the percentage fall of 6MWD with cardiopulmonary bypass (CPB) and preoperative inspiratory muscle strength. Receiver operating characteristic curve analysis revealed that the best cutoff value of percentage fall in 6MWD to predict poorer clinical outcomes at three months was 34.6% (area under the curve = 0.82, sensitivity = 78.95%, specificity = 76.19%, P=0.0001). Conclusion: This study indicates that a cutoff value of 34.6% in percentage fall of 6MWD on POD5 was able to predict poorer clinical outcomes at three months of follow-up after CABG. Use of CPB and preoperative inspiratory muscle strength were independent predictors of percentage fall of 6MWD in the postoperative period. These findings further support the clinical application of 6MWD and propose an inpatient preventive strategy to guide clinical management over time.

7.
Enferm Clin (Engl Ed) ; 32(2): 115-122, 2022.
Artigo em Espanhol | MEDLINE | ID: mdl-35577408

RESUMO

OBJECTIVE: To assess levels of medication adherence to antiplatelet and statins therapy among acute coronary syndrome (ACS) patients 30 days after hospital discharge and identify the main barriers to medication adherence and the main sociodemographic and clinical variables associated with treatment adherence. METHOD: This was a quantitative longitudinal study. Patients admitted to hospital with ACS were included. Initially, data collection was conducted using a semi-structured interview during the hospital stay. Thirty days after hospital discharge, the Brief Medication Questionnaire was applied by phone to assess treatment adherence. Descriptive statistics were used and tests were applied to analyze the association between medication adherence and clinical and sociodemographic data. RESULTS: One hundred and sixty-two patients were assessed. The Brief Medication Questionnaire test showed that 49.3% presented probable low adherence to treatment. Marital status, household income and alcohol intake showed an association with medication adherence. CONCLUSIONS: The findings of the present study indicate high rates of probable nonadherence to medication among ACS patients 30 days after hospital discharge, this information could help nurses to choose specific nursing interventions that could improve adherence in patients' daily routines.


Assuntos
Síndrome Coronariana Aguda , Inibidores de Hidroximetilglutaril-CoA Redutases , Síndrome Coronariana Aguda/tratamento farmacológico , Humanos , Inibidores de Hidroximetilglutaril-CoA Redutases/uso terapêutico , Estudos Longitudinais , Adesão à Medicação , Alta do Paciente
8.
Enferm. clín. (Ed. impr.) ; 32(2): 1-8, Mar - Abr, 2022. tab
Artigo em Espanhol | IBECS | ID: ibc-203652

RESUMO

Objetivo: Evaluar los niveles de adherencia a la terapia antiplaquetaria y a las estatinas por pacientes con síndrome coronario agudo (SCA) a los 30 días tras el alta hospitalaria e identificar las principales barreras y las principales variables sociodemográficas y clínicas asociadas con la adherencia al tratamiento.Método:Estudio longitudinal cuantitativo. Se incluyó a pacientes ingresados en un hospital con SCA. Inicialmente, la recolección de datos se realizó mediante una entrevista semiestructurada durante la estancia hospitalaria. A los 30 días tras el alta hospitalaria se aplicó el Brief Medication Questionnarie por teléfono, para evaluar la adherencia al tratamiento. Se utilizó estadística descriptiva y se aplicaron pruebas para analizar la asociación entre la adherencia a la medicación y los datos clínicos y sociodemográficos.Resultados: Ciento sesenta y dos pacientes fueron evaluados. El Brief Medication Questionnarie mostró que el 49,3% presentaba probable baja adherencia al tratamiento. El estado civil, el ingreso familiar y el consumo de alcohol tuvieron asociación con la adherencia a la medicación.Conclusiones: Los hallazgos del presente estudio indican altas tasas de probable falta de adherencia a la medicación por los pacientes con SCA a los 30 días tras el alta hospitalaria. Esta información podría ayudar a las enfermeras a elegir intervenciones específicas que puedan mejorar la adherencia en las rutinas diarias del paciente.


Objective: To assess levels of medication adherence to antiplatelet and statins therapy among acute coronary syndrome (ACS) patients 30 days after hospital discharge and identify the main barriers to medication adherence and the main sociodemographic and clinical variables associated with treatment adherence.Method: This was a quantitative longitudinal study. Patients admitted to hospital with ACS were included. Initially, data collection was conducted using a semi-structured interview during the hospital stay. Thirty days after hospital discharge, the Brief Medication Questionnaire was applied by phone to assess treatment adherence. Descriptive statistics were used and tests were applied to analyze the association between medication adherence and clinical and sociodemographic data.Results: One hundred and sixty-two patients were assessed. The Brief Medication Questionnaire test showed that 49.3% presented probable low adherence to treatment. Marital status, household income and alcohol intake showed an association with medication adherence.Conclusions: The findings of the present study indicate high rates of probable nonadherence to medication among ACS patients 30 days after hospital discharge, this information could help nurses to choose specific nursing interventions that could improve adherence in patients’ daily routines.


Assuntos
Humanos , Inibidores de Hidroximetilglutaril-CoA Redutases , Síndrome Coronariana Aguda , Tratamento Farmacológico , Alta do Paciente , Cooperação e Adesão ao Tratamento , Enfermagem , Papel do Profissional de Enfermagem , Enfermeiras e Enfermeiros , Doenças Cardiovasculares , Terapêutica/efeitos adversos
9.
Gomes, Walter J.; Rocco, Isadora; Pimentel, Wallace S.; Pinheiro, Aislan H. B.; Souza, Paulo M. S.; Costa, Luiz A. A.; Teixeira, Marjory M. P.; Ohashi, Leonardo P.; Bublitz, Caroline; Begot, Isis; Moreira, Rita Simone L; Hossne Jr, Nelson A.; Vargas, Guilherme F.; Branco, João Nelson R.; Teles, Carlos A.; Medeiros, Eduardo A. S.; Sáfadi, Camila; Rampinelli, Amândio; Moratelli Neto, Leopoldo; Rosado, Anderson Rosa; Mesacasa, Franciele Kuhn; Capriata, Ismael Escobar; Segalote, Rodrigo Coelho; Palmieri, Deborah Louize da Rocha Vianna; Jardim, Amanda Cristina Mendes; Vianna, Diego Sarty; Coutinho, Joaquim Henrique de Souza Aguiar; Jazbik, João Carlos; Coutinho, Henrique Madureira da Rocha; Kikuta, Gustavo; Almeida, Zely SantAnna Marotti de; Feguri, Gibran Roder; Lima, Paulo Ruiz Lucio de; Franco, Anna Carolina; Borges, Danilo de Cerqueira; Cruz, Felipe Ramos Honorato De La; Croti, Ulisses Alexandre; Borim, Bruna Cury; Marchi, Carlos Henrique De; Goraieb, Lilian; Postigo, Karolyne Barroca Sanches; Jucá, Fabiano Gonçalves; Oliveira, Fátima Rosane de Almeida; Souza, Rafael Bezerra de; Zilli, Alexandre Cabral; Mas, Raul Gaston Sanchez; Bettiati Junior, Luiz Carlos; Tranchesi, Ricardo; Bertini Jr, Ayrton; Franco, Leandro Vieira; Fernandes, Priscila; Oliveira, Fabiana; Moraes Jr, Roberto; Araújo, Thiago Cavalcanti Vila Nova de; Braga, Otávio Penna; Pedrosa Sobrinho, Antônio Cavalcanti; Teixeira, Roberta Tavares Barreto; Camboim, Irla Lavor Lucena; Gomes, Eduardo Nascimento; Reis, Pedro Horigushi; Garcia, Luara Piovan; Scorsioni, Nelson Henrique Goes; Lago, Roberto; Guizilini, Solange.
Rev. bras. cir. cardiovasc ; 36(6): 725-735, Nov.-Dec. 2021. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1351666

RESUMO

Abstract Introduction: We investigated the clinical course and outcomes of patients submitted to cardiovascular surgery in Brazil and who had developed symptoms/signs of coronavirus disease 2019 (COVID-19) in the perioperative period. Methods: A retrospective multicenter study including 104 patients who were allocated in three groups according to time of positive real time reverse transcriptase-polymerase chain reaction (RT-PCR) for the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2): group 1, patients who underwent cardiac surgery > 10 days after positive RT-PCR; group 2, patients with a positive RT-PCR within 10 days before or after surgery; group 3, patients who presented positive RT-PCR > 10 days after surgery. The primary outcome was mortality and secondary outcomes were postoperative complications, intensive care unit (ICU) length of stay, and postoperative days of hospitalization. Results: The three groups were similar with respect to age, the European System of Cardiac Operative Risk Evaluation score, and comorbidities, except hypertension. Postoperative complications and death were significantly higher in groups 2 and 3 than in group 1, and no significant difference between groups 2 and 3 was seen. Group 2 showed a high prevalence of surgery performed as an urgent procedure. Although no significant differences were observed in ICU length of stay, total postoperative hospitalization time was significantly higher in group 3 than in groups 1 and 2. Conclusion: COVID-19 affecting the postoperative period of patients who underwent cardiovascular surgery is associated with a higher rate of morbidity and mortality. Delaying procedures in RT-PCR-positive patients may help reduce risks of perioperative complications and death.


Assuntos
Humanos , COVID-19 , Brasil , Estudos Retrospectivos , Período Perioperatório , SARS-CoV-2
10.
Int J Cardiol ; 342: 34-38, 2021 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-34171450

RESUMO

BACKGROUND: Inflammation may be an important factor contributing to the progression of Eisenmenger syndrome (ES). The purpose of the current study was to: characterize the inflammatory profile in ES patients and compare measures to reference values for congenital heart disease and pulmonary arterial hypertension (CHD-PAH); and investigate whether inflammatory markers are associated with other clinical markers in ES. METHODS: Twenty-seven ES patients were prospectively selected and screened for systemic inflammatory markers, including interleukin (IL)-1ß, tumor necrosis factor-alpha (TNF-α) and IL-10. Clinical data and echocardiographic parameters were obtained, with concomitant analysis of ventricular function. Functional capacity was assessed using the 6-min walk test (6MWT). Renal function and blood homeostasis were evaluated by the level of blood urea nitrogen (BUN), creatinine, and plasma electrolytes. RESULTS: Patients with ES expressed higher IL-10, IL-1ß and TNF-α compared to reference values of patients with CHD-PAH. IL-10 was negatively associated with BUN (r = -0.39,p = 0.07), creatinine (r = -0.35, p = 0.002), sodium (r = -0.45, p = 0.03), and potassium (r = -0.68, p = 0.003). IL-10 was positively associated with bicarbonate (r = 0.45, p = 0.02) and trended toward a positive association with right ventricular fractional area change (RVFAC) (r = 0.35, p = 0.059). IL-1ß was negatively associated with potassium (r = -0.5, p = 0.01). TNF-α demonstrated positive association with creatinine (r = 0.4,p = 0.006), BUN (r = 0.63,p = 0.003), sodium (r = 0.44, p = 0.04), potassium (r = 0.41, p = 0.04), and was negatively associated with RVFAC (r = -0.38,p = 0.03) and 6MWT distance (r = -0.54, p = 0.004). CONCLUSION: ES patients exhibit a more severe inflammatory profile compared to reference values for CHD-PAH. Furthermore, inflammatory markers are related to renal dysfunction, right ventricular impairment and poorer functional capacity.


Assuntos
Complexo de Eisenmenger , Hipertensão Pulmonar , Biomarcadores , Estudos Transversais , Complexo de Eisenmenger/diagnóstico por imagem , Hipertensão Pulmonar Primária Familiar , Humanos
11.
Rev. bras. cir. cardiovasc ; 36(3): 308-317, May-June 2021. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1288237

RESUMO

Abstract Introduction: In heart transplantation (HT) recipients, several factors are critical to promptly adopting appropriate rehabilitation strategies and may be important to predict outcomes way after surgery. This study aimed to determine preoperative patient-related risk factors that could adversely affect the postoperative clinical course of patients undergoing HT. Methods: Twenty-one hospitalized patients with heart failure undergoing HT were evaluated according to respiratory muscle strength and functional capacity before HT. Mechanical ventilation (MV) time, reintubation rate, and intensive care unit (ICU) length of stay were recorded, and assessed postoperatively. Results: Inspiratory muscle strength as absolute and percentpredicted values were strongly correlated with MV time (r=-0.61 and r=-0.70, respectively, at P<0.001). Concerning ICU length of stay, only maximal inspiratory pressure (MIP) absolute and percent-predicted values were significantly associated. The absolute -MIP- was significantly negatively correlated with ICU length of stay (r=-0.58 at P=0.006) and the percent-predicted MIP was also significantly negatively correlated with ICU length of stay (r=-0.68 at P=0.0007). No associations were observed between preoperative functional capacity, age, sex, and clinical characteristics and MV time and ICU length of stay in the cohort included in this study. Patients with respiratory muscle weakness had a higher prevalence of prolonged MV, reintubation, and delayed ICU length of stay. Conclusion: An impairment of preoperative MIP was associated with poorer short-term outcomes following HT. As such, inspiratory muscle strength is an important clinical preoperative marker in patients undergoing HT.


Assuntos
Transplante de Coração , Debilidade Muscular/etiologia , Respiração Artificial , Músculos Respiratórios , Pressões Respiratórias Máximas , Unidades de Terapia Intensiva
12.
Expert Rev Anti Infect Ther ; 19(11): 1385-1396, 2021 11.
Artigo em Inglês | MEDLINE | ID: mdl-33852807

RESUMO

Introduction: The coronavirus disease-2019 (COVID-19) is a highly contagious respiratory viral disease for both the general population and healthcare professionals caring for infected patients. Of particular concern is the potential for significant respiratory, cardiovascular, physical, and psychological dysfunctions.Areas covered: In this context, the current review will focus on the following areas: 1) staying physically active during the COVID-19 pandemic; 2) highlighting the importance of understanding COVID-19 mechanisms; 3) preventing infections for healthcare workers by using personal protective equipment; 4) highlighting importance of respiratory care and physical therapy during hospitalization in patients with COVID-19; and 5) facilitating referral to a rehabilitation program in patients recovering from COVID-19.Expert opinion: We recommend daily physical exercise, outdoors or at home, as physical exercise increases the synthesis of anti-inflammatory cytokines; Patients with COVID-19 may develop severe acute respiratory syndrome, hypoxemia, diffuse alveolar damage, ACE2 reduction in the cardiovascular system and muscle weakness acquired through a prolonged hospital stay; The role of the physiotherapist in the hospital environment is of fundamental importance-early mobilization is highly recommended in severe cases of COVID-19.


Assuntos
COVID-19 , Terapia por Exercício , Estilo de Vida , Pandemias , Reabilitação/organização & administração , Exercício Físico , Pessoal de Saúde , Humanos
13.
Braz J Cardiovasc Surg ; 36(3): 308-317, 2021 06 01.
Artigo em Inglês | MEDLINE | ID: mdl-33438847

RESUMO

INTRODUCTION: In heart transplantation (HT) recipients, several factors are critical to promptly adopting appropriate rehabilitation strategies and may be important to predict outcomes way after surgery. This study aimed to determine preoperative patient-related risk factors that could adversely affect the postoperative clinical course of patients undergoing HT. METHODS: Twenty-one hospitalized patients with heart failure undergoing HT were evaluated according to respiratory muscle strength and functional capacity before HT. Mechanical ventilation (MV) time, reintubation rate, and intensive care unit (ICU) length of stay were recorded, and assessed postoperatively. RESULTS: Inspiratory muscle strength as absolute and percentpredicted values were strongly correlated with MV time (r=-0.61 and r=-0.70, respectively, at P<0.001). Concerning ICU length of stay, only maximal inspiratory pressure (MIP) absolute and percent-predicted values were significantly associated. The absolute |MIP| was significantly negatively correlated with ICU length of stay (r=-0.58 at P=0.006) and the percent-predicted MIP was also significantly negatively correlated with ICU length of stay (r=-0.68 at P=0.0007). No associations were observed between preoperative functional capacity, age, sex, and clinical characteristics and MV time and ICU length of stay in the cohort included in this study. Patients with respiratory muscle weakness had a higher prevalence of prolonged MV, reintubation, and delayed ICU length of stay. CONCLUSION: An impairment of preoperative MIP was associated with poorer short-term outcomes following HT. As such, inspiratory muscle strength is an important clinical preoperative marker in patients undergoing HT.


Assuntos
Transplante de Coração , Debilidade Muscular , Humanos , Unidades de Terapia Intensiva , Pressões Respiratórias Máximas , Debilidade Muscular/etiologia , Respiração Artificial , Músculos Respiratórios
14.
Braz J Cardiovasc Surg ; 35(4): 530-538, 2020 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-32864934

RESUMO

In December 2019, a striking appearance of new cases of viral pneumonia in Wuhan led to the detection of a novel coronavirus (SARS-CoV2). By analyzing patients with severe manifestations, it became apparent that 20 to 35% of patients who died had preexisting cardiovascular disease. This finding warrants the important need to discuss the influence of SARS-CoV2 infection on the cardiovascular system and hemodynamics in the context of clinical management, particularly during mechanical ventilation. The SARS-CoV2 enters human cells through the spike protein binding to angiotensin-converting enzyme 2 (ACE2), which is important to cardiovascular modulation and endothelial signaling. As ACE2 is highly expressed in lung tissue, patients have been progressing to acute respiratory injury at an alarming frequency during the Coronavirus Disease (COVID-19) pandemic. Moreover, COVID-19 leads to high D-dimer levels and prothrombin time, which indicates a substantial coagulation disorder. It seems that an overwhelming inflammatory and thrombogenic condition is responsible for a mismatching of ventilation and perfusion, with a somewhat near-normal static lung compliance, which describes two types of pulmonary conditions. As such, positive pressure during invasive mechanical ventilation (IMV) must be applied with caution. The authors of this review appeal to the necessity of paying closer attention to assess microhemodynamic repercussion, by monitoring central venous oxygen saturation during strategies of IMV. It is well known that a severe respiratory infection and a scattered inflammatory process can cause non-ischemic myocardial injury, including progression to myocarditis. Early strategies that guide clinical decisions can be lifesaving and prevent extended myocardial damage. Moreover, cardiopulmonary failure refractory to standard treatment may necessitate the use of extreme therapeutic strategies, such as extracorporeal membrane oxygenation.


Assuntos
Sistema Cardiovascular/virologia , Infecções por Coronavirus/complicações , Hemodinâmica , Pneumonia Viral/complicações , Betacoronavirus , COVID-19 , Sistema Cardiovascular/fisiopatologia , Humanos , Miocárdio/patologia , Pandemias , Respiração Artificial , SARS-CoV-2
15.
Rev. bras. cir. cardiovasc ; 35(4): 530-538, July-Aug. 2020. tab, graf
Artigo em Inglês | Sec. Est. Saúde SP, LILACS | ID: biblio-1137302

RESUMO

Abstract In December 2019, a striking appearance of new cases of viral pneumonia in Wuhan led to the detection of a novel coronavirus (SARS-CoV2). By analyzing patients with severe manifestations, it became apparent that 20 to 35% of patients who died had preexisting cardiovascular disease. This finding warrants the important need to discuss the influence of SARS-CoV2 infection on the cardiovascular system and hemodynamics in the context of clinical management, particularly during mechanical ventilation. The SARS-CoV2 enters human cells through the spike protein binding to angiotensin-converting enzyme 2 (ACE2), which is important to cardiovascular modulation and endothelial signaling. As ACE2 is highly expressed in lung tissue, patients have been progressing to acute respiratory injury at an alarming frequency during the Coronavirus Disease (COVID-19) pandemic. Moreover, COVID-19 leads to high D-dimer levels and prothrombin time, which indicates a substantial coagulation disorder. It seems that an overwhelming inflammatory and thrombogenic condition is responsible for a mismatching of ventilation and perfusion, with a somewhat near-normal static lung compliance, which describes two types of pulmonary conditions. As such, positive pressure during invasive mechanical ventilation (IMV) must be applied with caution. The authors of this review appeal to the necessity of paying closer attention to assess microhemodynamic repercussion, by monitoring central venous oxygen saturation during strategies of IMV. It is well known that a severe respiratory infection and a scattered inflammatory process can cause non-ischemic myocardial injury, including progression to myocarditis. Early strategies that guide clinical decisions can be lifesaving and prevent extended myocardial damage. Moreover, cardiopulmonary failure refractory to standard treatment may necessitate the use of extreme therapeutic strategies, such as extracorporeal membrane oxygenation.


Assuntos
Humanos , Pneumonia Viral/complicações , Sistema Cardiovascular/virologia , Infecções por Coronavirus/complicações , Hemodinâmica , Respiração Artificial , Sistema Cardiovascular/fisiopatologia , Infecções por Coronavirus , Pandemias , Betacoronavirus , Miocárdio/patologia
16.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-32273168

RESUMO

OBJECTIVE: To assess levels of medication adherence to antiplatelet and statins therapy among acute coronary syndrome (ACS) patients 30 days after hospital discharge and identify the main barriers to medication adherence and the main sociodemographic and clinical variables associated with treatment adherence. METHOD: This was a quantitative longitudinal study. Patients admitted to hospital with ACS were included. Initially, data collection was conducted using a semi-structured interview during the hospital stay. Thirty days after hospital discharge, the Brief Medication Questionnaire was applied by phone to assess treatment adherence. Descriptive statistics were used and tests were applied to analyze the association between medication adherence and clinical and sociodemographic data. RESULTS: One hundred and sixty-two patients were assessed. The Brief Medication Questionnaire test showed that 49.3% presented probable low adherence to treatment. Marital status, household income and alcohol intake showed an association with medication adherence. CONCLUSIONS: The findings of the present study indicate high rates of probable nonadherence to medication among ACS patients 30 days after hospital discharge, this information could help nurses to choose specific nursing interventions that could improve adherence in patients' daily routines.

17.
Braz J Cardiovasc Surg ; 35(1): 82-90, 2020 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-32270964

RESUMO

OBJECTIVE: To analyze the profile and outcomes of patients who underwent valve heart surgery in Brazil, using information retrieved from the Brazilian Registry of Cardiovascular Surgeries in Adults (BYPASS Registry) database. METHODS: This is a multicenter cohort study, evaluating 920 patients submitted to heart valve surgery. Demographics and postoperative clinical outcomes were assessed and compared to estimate mortality risk using the European System for Cardiac Operative Risk Evaluation (EuroSCORE). RESULTS: Isolated aortic valve replacement was the most frequently performed surgery (34%), followed by isolated mitral valve replacement (24.9%). Valve repair was performed in 21% of mitral procedures. Minimally invasive access was performed in 1.6% and the most frequent postoperative complications were arrhythmias (22.6%), infections (5.7%), and low-output syndrome (5.1%). Operations covered by the public health system accounted for 80.8% and the hospital mortality rate was 7.3%. CONCLUSION: The most frequent isolated valve surgery in Brazil is the aortic valve replacement by conventional open access and the rheumatic disease is still the main etiology for valve surgery. The BYPASS Registry has a fundamental role to provide information on the profile of patients with valve heart disease in our country in order to delineate adequate strategies for health promotion and resource allocation for cardiac surgery.


Assuntos
Procedimentos Cirúrgicos Cardíacos , Adulto , Idoso , Brasil , Estudos de Coortes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias , Sistema de Registros , Estudos Retrospectivos , Resultado do Tratamento
18.
Esc. Anna Nery Rev. Enferm ; 24(spe): e20200296, 20200000. graf, tab
Artigo em Português | BDENF - Enfermagem | ID: biblio-1146028

RESUMO

Introdução: Com o início da pandemia, inquietações quanto à condução da parada cardiorrespiratória em casos suspeitos e confirmados da COVID-19 surgiram ante as peculiaridades e publicações científicas quanto à temática. Dessa forma, o presente estudo apresenta uma reflexão e demonstra as novas recomendações acerca dos cuidados necessários a serem adotados pela equipe multiprofissional. Método: Trata-se de um estudo de reflexão teórica, de caráter descritivo e abordagem qualitativa com base em documentos convencionais e não convencionais emitidos pelos principais órgãos reguladores e revistas de grande impacto que abordam as temáticas discorridas. Além disso, não houve recorte temporal para a seleção do referencial bibliográfico. Resultados: Os resultados expostos abordaram o cuidado relacionado com os recursos humanos e materiais envolvendo a temática, o manejo da via aérea nesse evento em pacientes que estavam ou não em uso de intubação endotraqueal, assim como em relação aos indivíduos em posição prona. Conclusão e implicações para a prática: Diante das discussões apresentadas, é evidente a necessidade de atualização por parte das instituições de saúde em suas rotinas e dos profissionais que se encontram neste estudo como mecanismo de proteção e manutenção da qualidade do cuidado prestado


Introduction: With the onset of the pandemic, concerns emerged about the management of cardiorespiratory arrest in suspected and confirmed cases of COVID-19 considering its singularities and scientific publications on the subject. Thus, this study presents a reflection about the new recommendations for patient care that must be adopted by multiprofessional teams. Method: This is a theoretical qualitative descriptive study that analyzed conventional and unconventional documents issued by the main regulatory bodies and high impact magazines addressing the study topics. No time frame was considered when selecting the bibliographic references. Results: The results addressed patient care with human and material resources involving the theme, the airway management in patients affected by COVID-19, whether they were using endotracheal intubation or not, and the approach for individuals in prone position. Conclusion and implications for the practice: In view of the discussions presented, health institutions and professionals must update their routines as a mechanism to protect and maintain the quality of care provided


Introducción: Con el inicio de la pandemia, preocupaciones sobre la conducción del paro cardiorrespiratorio en casos sospechosos y confirmados de COVID-19 ante las peculiaridades y publicaciones científicas sobre el tema. Así pues, este estudio presenta una reflexión y demuestra las nuevas recomendaciones sobre los cuidados que deben adoptarse por el equipo. Método: Se trata de un estudio de reflexión teórica, de carácter descriptivo y enfoque cualitativo, basado em documentos convencionales y no convencionales emitidos por los principales organismos reguladores y revistas de alto impacto que abordan los temas tratados. Además, no hubo un recorte temporal para la selección de la referencia bibliográfica. Resultados: Los resultados expuestos abordaron el cuidado relacionado con los recursos humanos y materiales involucrando la temática, el manejo de la vía aérea en este evento, en pacientes que usaban o no intubación endotraqueal, como también en relación de individuos en posición prona. Conclusión e implicaciones para la práctica: Ante las discusiones presentadas, es evidente la necesidad de actualización por las instituciones de salud en sus rutinas y de los profesionales que se encuentran en este estudio, como mecanismo de protección y mantenimiento de la calidad del cuidado ministrado


Assuntos
Humanos , Equipe de Assistência ao Paciente , Reanimação Cardiopulmonar/normas , Transmissão de Doença Infecciosa do Paciente para o Profissional/prevenção & controle , COVID-19/prevenção & controle , Parada Cardíaca/reabilitação , Riscos Ocupacionais , Equipamento de Proteção Individual
19.
Rev. bras. cir. cardiovasc ; 35(1): 82-90, Jan.-Feb. 2020. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1092463

RESUMO

Abstract Objective: To analyze the profile and outcomes of patients who underwent valve heart surgery in Brazil, using information retrieved from the Brazilian Registry of Cardiovascular Surgeries in Adults (BYPASS Registry) database. Methods: This is a multicenter cohort study, evaluating 920 patients submitted to heart valve surgery. Demographics and postoperative clinical outcomes were assessed and compared to estimate mortality risk using the European System for Cardiac Operative Risk Evaluation (EuroSCORE). Results: Isolated aortic valve replacement was the most frequently performed surgery (34%), followed by isolated mitral valve replacement (24.9%). Valve repair was performed in 21% of mitral procedures. Minimally invasive access was performed in 1.6% and the most frequent postoperative complications were arrhythmias (22.6%), infections (5.7%), and low-output syndrome (5.1%). Operations covered by the public health system accounted for 80.8% and the hospital mortality rate was 7.3%. Conclusion: The most frequent isolated valve surgery in Brazil is the aortic valve replacement by conventional open access and the rheumatic disease is still the main etiology for valve surgery. The BYPASS Registry has a fundamental role to provide information on the profile of patients with valve heart disease in our country in order to delineate adequate strategies for health promotion and resource allocation for cardiac surgery.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Procedimentos Cirúrgicos Cardíacos , Complicações Pós-Operatórias , Brasil , Sistema de Registros , Estudos Retrospectivos , Estudos de Coortes , Resultado do Tratamento
20.
Braz J Cardiovasc Surg ; 34(4): 484-487, 2019 08 27.
Artigo em Inglês | MEDLINE | ID: mdl-31454204

RESUMO

Placement of a mediastinal drain is a routine procedure following heart surgery. Postoperative bed rest is often imposed due to the fear of potential risk of drain displacement and cardiac injury. We developed an encapsulating stitch as a feasible, effective and low-cost technique, which does not require advanced surgical skills for placement. This simple, novel approach compartmentalizes the drain allowing for safe early mobilization following cardiac surgery.


Assuntos
Ponte de Artéria Coronária , Drenagem/instrumentação , Monitorização Neurofisiológica Intraoperatória/métodos , Mediastino/cirurgia , Complicações Pós-Operatórias/prevenção & controle , Drenagem/métodos , Estudos de Viabilidade , Ventrículos do Coração/lesões , Humanos , Derrame Pericárdico/prevenção & controle
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